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Chapter 14: Pain Response Drugs

14 problems · 0 figures

Case Study 14.2.1 §14.2 source ↗

Read the following clinical scenario to answer the questions that follow. This case study will evolve throughout the chapter.

Maria Vega is a 63-year-old client who presents to her health care provider’s office with reports of abdominal pain, diarrhea that is occasionally black and tarry in appearance, and dizziness.

History
Coronary artery disease
Osteoarthritis (both knees and hips are affected)

Current Medications
Aspirin 81 mg orally once daily
Metoprolol 50 mg orally twice daily
Over-the-counter ibuprofen 400 mg orally every 4–6 hours as needed for joint pain

Based on the information above, what is the most important question for the nurse to ask Maria?
  1. a.
    “How long have you been taking aspirin?”
  2. b.
    “How many stools have you had today?”
  3. c.
    “How much ibuprofen do you take each day?”
  4. d.
    “Have you lost any weight in the last month?”
Table 14.3 in the book ↗
Vital Signs Physical Examination
Temperature: 98.8°F

• Head, eyes, ears, nose, throat (HEENT): Within normal limits

• Cardiovascular: No jugular vein distention; no peripheral edema noted bilaterally; S1, S2 auscultated, rhythm regular

• Respiratory: Lungs clear to auscultation bilaterally

• GI: Abdomen soft, generalized tenderness, nondistended;
normal bowel sounds auscultated in all four quadrants

• GU: Reports normal urine output

• Neurologic: Within normal limits

• Integumentary: No wounds noted; skin appropriate for age

Blood pressure: 126/86 mm Hg
Heart rate: 74 beats/min
Respiratory rate: 16 breaths/min
Oxygen saturation: 97% on room air
Height: 5'3"
Weight: 122 lb

Answer

C. “How much ibuprofen do you take each day?”
Because this client is taking both aspirin and ibuprofen (which are both NSAIDs), and because she is taking ibuprofen on an as-needed basis, it is important to determine how much ibuprofen the client is taking.

Case Study 14.2.2 §14.2 source ↗

Read the following clinical scenario to answer the questions that follow. This case study will evolve throughout the chapter.

Maria Vega is a 63-year-old client who presents to her health care provider’s office with reports of abdominal pain, diarrhea that is occasionally black and tarry in appearance, and dizziness.

History
Coronary artery disease
Osteoarthritis (both knees and hips are affected)

Current Medications
Aspirin 81 mg orally once daily
Metoprolol 50 mg orally twice daily
Over-the-counter ibuprofen 400 mg orally every 4–6 hours as needed for joint pain

The nurse determines that the client is taking 2 or 3 200 mg tablets nine times daily to control her arthritic pain. Which instruction should the nurse give the client?
  1. a.
    “This dose is too low to effectively relieve arthritis pain.”
  2. b.
    “This dose is appropriate for arthritis pain.”
  3. c.
    “This dose may cause respiratory depression.”
  4. d.
    “This dose is too high and can cause gastric bleeding.”
Table 14.3 in the book ↗
Vital Signs Physical Examination
Temperature: 98.8°F

• Head, eyes, ears, nose, throat (HEENT): Within normal limits

• Cardiovascular: No jugular vein distention; no peripheral edema noted bilaterally; S1, S2 auscultated, rhythm regular

• Respiratory: Lungs clear to auscultation bilaterally

• GI: Abdomen soft, generalized tenderness, nondistended;
normal bowel sounds auscultated in all four quadrants

• GU: Reports normal urine output

• Neurologic: Within normal limits

• Integumentary: No wounds noted; skin appropriate for age

Blood pressure: 126/86 mm Hg
Heart rate: 74 beats/min
Respiratory rate: 16 breaths/min
Oxygen saturation: 97% on room air
Height: 5'3"
Weight: 122 lb

Answer

D. “This dose is too high and can cause gastric bleeding.”
This dose exceeds the 3200 mg maximum dose for ibuprofen and, based on the client’s report of black tarry stools, has already caused gastric bleeding.

Case Study 14.3.3 §14.3 source ↗

Read the following clinical scenario to answer the questions that follow. This case study is a follow-up to Unfolding Case Study Part A.

Two months after the last encounter, Maria Vega presents to the emergency department following a fall at home. She rates her right ankle pain as 6/10 on a 0- to 10-point pain scale. She is diagnosed with a right ankle fracture.

History
Coronary artery disease
Osteoarthritis

Current Medications
Aspirin 81 mg orally once daily
Metoprolol 50 mg orally twice daily
Over-the-counter ibuprofen 400 mg orally every 4–6 hours as needed for joint pain

Based on the information above, which medication does the nurse anticipate the provider will order for the client’s pain?
  1. a.
    Acetaminophen
  2. b.
    Ibuprofen
  3. c.
    Hydromorphone
  4. d.
    Meperidine
Table 14.6 in the book ↗
Vital Signs Physical Examination
Temperature: 97.4°F

• Head, eyes, ears, nose, throat (HEENT): Within normal limits

• Cardiovascular: No jugular vein distention; no peripheral edema noted bilaterally; S1, S2 auscultated; rhythm regular

• Respiratory: Lung clear to auscultation bilaterally

• GI: Abdomen soft, nontender, nondistended; normal bowel sounds auscultated in all four quadrants

• GU: Reports normal urine output

• Neurologic: Within normal limits

• Integumentary: No wounds noted; skin appropriate for age

• Extremities: Right ankle in a splint, toes are pink; dorsalis pedis pulses strong bilaterally; able to feel light touch and wiggle toes of right foot

Blood pressure: 146/66 mm Hg
Heart rate: 93 beats/min
Respiratory rate: 18 breaths/min
Oxygen saturation: 96% on room air
Height: 5'3"
Weight: 122 lb

Answer

C. Hydromorphone
Hydromorphone is a semisynthetic derivative of morphine that is used to treat moderate to severe pain.

Case Study 14.3.4 §14.3 source ↗

Read the following clinical scenario to answer the questions that follow. This case study is a follow-up to Unfolding Case Study Part A.

Two months after the last encounter, Maria Vega presents to the emergency department following a fall at home. She rates her right ankle pain as 6/10 on a 0- to 10-point pain scale. She is diagnosed with a right ankle fracture.

History
Coronary artery disease
Osteoarthritis

Current Medications
Aspirin 81 mg orally once daily
Metoprolol 50 mg orally twice daily
Over-the-counter ibuprofen 400 mg orally every 4–6 hours as needed for joint pain

The health care provider prescribes hydromorphone for the client’s ankle pain. Which information will the nurse give the client about this drug?
  1. a.
    “Do not drink alcohol while you’re taking this medication.”
  2. b.
    “Reduce your fiber intake while taking this medication.”
  3. c.
    “Your heart rate might slow down when you’re taking this medication.”
  4. d.
    “This medication might lower your blood pressure.”
Table 14.6 in the book ↗
Vital Signs Physical Examination
Temperature: 97.4°F

• Head, eyes, ears, nose, throat (HEENT): Within normal limits

• Cardiovascular: No jugular vein distention; no peripheral edema noted bilaterally; S1, S2 auscultated; rhythm regular

• Respiratory: Lung clear to auscultation bilaterally

• GI: Abdomen soft, nontender, nondistended; normal bowel sounds auscultated in all four quadrants

• GU: Reports normal urine output

• Neurologic: Within normal limits

• Integumentary: No wounds noted; skin appropriate for age

• Extremities: Right ankle in a splint, toes are pink; dorsalis pedis pulses strong bilaterally; able to feel light touch and wiggle toes of right foot

Blood pressure: 146/66 mm Hg
Heart rate: 93 beats/min
Respiratory rate: 18 breaths/min
Oxygen saturation: 96% on room air
Height: 5'3"
Weight: 122 lb

Answer

A. “Do not drink alcohol while you’re taking this medication.”
The use of an opioid, such as hydromorphone, with alcohol can result in sedation and respiratory depression.

14-1 §14.RQ source ↗

A client presents to the clinic reporting dull, throbbing left leg pain, rated as 4/10 on a 0–10 pain scale. They have been experiencing this for the past year following a leg fracture in a car collision. The nurse determines that this client is experiencing which type of pain?
  1. a.
    Acute pain
  2. b.
    Chronic pain
  3. c.
    Neuropathic pain
  4. d.
    Severe pain

Answer

B. Chronic pain
The client’s pain is considered chronic because it has been going on for more than 3 months.

14-2 §14.RQ source ↗

A client who had a cholecystectomy earlier in the day asks the nurse for pain medication for pain rated as 6/10 on a 0–10 pain rating scale. When the nurse returns with the pain medication, the client is chatting and laughing with a visitor. Which action should the nurse take?
  1. a.
    Assume that the client is not in pain
  2. b.
    Determine that the client was not rating their pain correctly
  3. c.
    Administer the pain medication
  4. d.
    Challenge the client’s pain rating

Answer

C. Administer the pain medication
Pain is a subjective rating, and the nurse should define pain as “whatever the client says it is.” Therefore, the nurse should administer the pain medication.

14-3 §14.RQ source ↗

A client with no past medical history is prescribed acetaminophen, as needed, for pain related to starting a new workout regimen. They have acetaminophen 500 mg tablets at home. The nurse instructs the client not to exceed how many tablets per day?
  1. a.
    10
  2. b.
    12
  3. c.
    6
  4. d.
    8

Answer

D. 8
Eight tablets of 500 mg acetaminophen is 4000 mg, which is the amount of acetaminophen that should not be exceeded in a day.

14-4 §14.RQ source ↗

The health care provider has recommended that a client begin taking an anti-inflammatory drug to reduce the pain of osteoarthritis. Which medication does the nurse anticipate the provider will order?
  1. a.
    Tramadol
  2. b.
    Naltrexone
  3. c.
    Ibuprofen
  4. d.
    Nalbuphine

Answer

C. Ibuprofen
Ibuprofen is the only option that is an anti-inflammatory drug.

14-5 §14.RQ source ↗

A 75-year-old client reports intermittent pain that ranges from 4 to 10 on a 0–10 scale. The client states that the pain started 5 years ago after they had herpes zoster (shingles). The nurse understands that this pain is classified as which of the following types?
  1. a.
    Nociceptive
  2. b.
    Neuropathic
  3. c.
    Acute
  4. d.
    Visceral

Answer

B. Neuropathic
The affected nerves were damaged by the varicella-zoster virus. Shingles pain, or postherpetic neuralgia, develops in up to 50% of individuals over the age of 65 who contract the disease.

14-6 §14.RQ source ↗

The nurse administers morphine intravenously to a postoperative client and returns 20 minutes later to reassess the client. The nurse observes the client taking slow and shallow breaths, and they are unresponsive to verbal and physical stimuli. The nurse activates the rapid response team and prepares to administer which medication?
  1. a.
    Tramadol
  2. b.
    Naloxone
  3. c.
    Acetaminophen
  4. d.
    Methadone

Answer

B. Naloxone
Naloxone works as an opioid receptor antagonist and is the drug of choice to quickly reverse the effects of opioid intoxication, which is indicated here by the client’s unresponsiveness and shallow breathing.

14-7 §14.RQ source ↗

A nurse in an emergency department is taking a medication history on a new client. The client reports previously experiencing flushing, itching, and low blood pressure after taking an opioid for pain caused by a bone fracture but does not recall the name of the medication. The nurse suspects that the client was most likely taking which opioid?
  1. a.
    Hydromorphone
  2. b.
    Methadone
  3. c.
    Oxycodone
  4. d.
    Morphine

Answer

D. Morphine
This client most likely experienced a reaction to histamine caused by morphine. This adverse reaction is most often seen with morphine and codeine, which is converted into morphine.

14-8 §14.RQ source ↗

A client with a history of opioid use disorder is prescribed naltrexone to aid in abstaining from opioid use. Which information will the nurse give the client?
  1. a.
    This drug reverses an accidental overdose.
  2. b.
    This drug blunts the effects of opioids.
  3. c.
    This drug can cause euphoria.
  4. d.
    This drug causes a high feeling.

Answer

B. This drug blunts the effects of opioids.
Naltrexone is an opioid antagonist that can be used orally and intramuscularly to aid clients who are attempting to quit using opioids. While the client is taking naltrexone, any opioids taken will not be able to activate opioid receptors, blunting the effects of opioids and the feelings of euphoria.

14-9 §14.RQ source ↗

A client reports that the current dosage of oxycodone they are taking for chronic back pain is no longer relieving the pain. The health care provider increases the dosage of oxycodone, and at a follow-up appointment the client reports that their pain is well controlled again. The nurse explains that the client is experiencing which phenomenon?
  1. a.
    Adverse reaction
  2. b.
    Tolerance
  3. c.
    Opioid use disorder
  4. d.
    Allergic reaction

Answer

B. Tolerance
Tolerance is a natural occurrence in clients receiving chronic opioid agonists. It frequently requires the dosage of the opioid agonist to be increased to achieve adequate pain management.

14-10 §14.RQ source ↗

A client recovering from a knee replacement in the postanesthesia care unit develops significant shivering. Which medication does the nurse anticipate will be ordered for this client?
  1. a.
    Aspirin
  2. b.
    Codeine
  3. c.
    Meperidine
  4. d.
    Nalbuphine

Answer

C. Meperidine
Severe shivering with chills (also known as rigors) may occur in clients who received anesthesia. The treatment of choice for this is meperidine. Because of the well-known toxicities of meperidine in older adults and those with poor renal function, it should almost never be used for pain.

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Problems and answers are adapted from Pharmacology for Nurses by Tina Barbour-Taylor, Leah Mueller (Sabato), Donna Paris and Dorie Weaver, OpenStax, and are used under the CC BY-NC-SA 4.0 licence. Access for free at https://openstax.org/books/pharmacology/pages/1-introduction. Illustrations: Copyright Rice University, OpenStax, under CC BY-NC-SA 4.0 license. This adaptation is released under the same licence, is non-commercial, and is neither affiliated with nor endorsed by OpenStax or Rice University.