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Chapter 17: Neuroimmunology

15 problems · 0 figures

17-1 §17.1 source ↗

The innate immune response:
  1. a.
    is specialized to each specific pathogen.
  2. b.
    ramps up slowly and adapts over time.
  3. c.
    has a similar response to all pathogens.
  4. d.
    uses T cells.

Answer

C. has a similar response to all pathogens.

17-3 §17.1 source ↗

Which of the following are ways macrophages attack pathogens?
  1. a.
    Eating pathogens
  2. b.
    Releasing complement proteins
  3. c.
    Showing a piece of the pathogen to adaptive immune cells so that they can attack it too
  4. d.
    All of these

Answer

D. All of these

17-5 §17.1 source ↗

T cells:
  1. a.
    make antibodies.
  2. b.
    directly kill infected cells.
  3. c.
    phagocytose pathogens.
  4. d.
    spit their DNA out in nets to draw pathogens in.

Answer

B. directly kill infected cells.

17-7 §17.1 source ↗

Recognizing self-antigens is critical to preventing your immune system from attacking your own cells. How do your cells tell T cells not to attack them?
  1. a.
    By presenting some self-antigen via MHC I
  2. b.
    By presenting some self-antigen via MHC II
  3. c.
    By presenting some pathogen antigen via MHC I
  4. d.
    By presenting some pathogen antigen via MHC II

Answer

A. By presenting some self-antigen via MHC I

17-9 §17.1 source ↗

Which cells will you find in the brain of a typical healthy human?
  1. a.
    Microglia
  2. b.
    Neutrophils
  3. c.
    T cells
  4. d.
    B cells

Answer

A. Microglia

17-11 §17.2 source ↗

Blocking the cytokine response to illness will most likely:
  1. a.
    increase sickness behaviors.
  2. b.
    decrease sickness behaviors.
  3. c.
    not affect sickness behaviors.

Answer

B. decrease sickness behaviors.

17-13 §17.2 source ↗

Which of the following diseases may be associated with immune dysfunction?
  1. a.
    Schizophrenia
  2. b.
    Depression
  3. c.
    PTSD
  4. d.
    All of these

Answer

D. All of these

17-15 §17.3 source ↗

Which of the following statements is false?
  1. a.
    The brain is immune privileged and has no immune response capabilities
  2. b.
    The brain has a lymphatic system that allows interaction of T cells with neurons
  3. c.
    The brain has resident immune cells that are critical to normal functioning and development
  4. d.
    The BBB prevents entry of most peripheral immune cells into the brain under normal conditions

Answer

A. The brain is immune privileged and has no immune response capabilities

17-17 §17.3 source ↗

Stress-induced activation of the immune system happens in response to which?
  1. a.
    Physical stressors like an injury
  2. b.
    Psychological stressors like sitting in traffic
  3. c.
    Both physical and psychological stressors
  4. d.
    Only the most severe stressors

Answer

C. Both physical and psychological stressors

17-19 §17.3 source ↗

What appears to be critical to the beneficial effects of exercise as a stressor that activates the immune system?
  1. a.
    Exercise has a clear resolution point at which the stressor ends and the immune activation resolves
  2. b.
    Exercise leads to a smaller immune response than other stressors
  3. c.
    Exercise lead to a larger immune response than other stressors
  4. d.
    Exercise does not activate the HPA

Answer

A. Exercise has a clear resolution point at which the stressor ends and the immune activation resolves

17-21 §17.4 source ↗

Microglia can:
  1. a.
    prune whole synapses.
  2. b.
    cleave specific proteins off synapses.
  3. c.
    eat cells and parts of cells.
  4. d.
    Do all of these things.

Answer

D. Do all of these things.

17-23 §17.4 source ↗

During development, neurons and microglia come from:
  1. a.
    neuroectoderm.
  2. b.
    the fetal yolk sack.
  3. c.
    different parts of the embryo.
  4. d.
    the endoderm.

Answer

C. different parts of the embryo.

Fill in the Blank 17.1 §17.1 source ↗

The two basic divisions of the immune system are the ________ and the ________.

Answer

innate / adaptive

Fill in the Blank 17.3 §17.2 source ↗

Isolating, loss of appetite, and feeling fatigue when we are sick are examples of ________.

Answer

sickness behaviors

Fill in the Blank 17.5 §17.4 source ↗

Microglia come from this early embryonic structure: ________.

Answer

fetal yolk sack

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Problems and answers are adapted from Introduction to Behavioral Neuroscience by Elizabeth D. Kirby, Melissa J. Glenn, Noah J. Sandstrom and Christina L. Williams, OpenStax, and are used under the CC BY-NC-SA 4.0 licence. Access for free at https://openstax.org/books/introduction-behavioral-neuroscience/pages/1-introduction. Illustrations: Copyright Rice University, OpenStax, under CC BY-NC-SA 4.0 license. This adaptation is released under the same licence, is non-commercial, and is neither affiliated with nor endorsed by OpenStax or Rice University.